Welcome to the Leigh & Lee DNA Clearing HouseWhat are haplogroups?

When people begin reading about the use of DNA in genealogy, they see references to haplogroups, and they wonder, "What are these haplogroup things?" This post gives a brief answer to that question.

People have traditionally performed genealogical research by studying written documents. A new dimension has been added to genealogical research: the use of DNA. Each person has a "blueprint" in their body that contains information or instructions for the makeup and operation of their body. That blueprint is called DNA.

DNA is passed from parent to child in two ways. The Y-chromosome, that is passed from father to son, carries DNA information, and this information is referred to as Y-DNA. DNA information is also passed from mother to daughter and is known mtDNA. Y-DNA is used in genealogy because it is passed from father to son, and genealogical research is based on father-to-child relationships. Genealogists are beginning to use mtDNA, but its use isn't as widespread as that of Y-DNA.

Included in DNA is information about the origin of some of the person's ancestors. Humans are believed to have originated in Africa. The DNA of those ancient people was passed on to their children. However, occasional changes or mutations in DNA occurred, and the changes were also passed on to their descendants. As people spread over the earth, changes to DNA caused distinct patterns of DNA segments to appear. Today, those patterns are called haplogroups, and they give a general idea where particular genealogical lines came from tens of thousands of years ago.

The following chart shows how various Y-DNA haplogroups have separated from the original haplogroup that was in Africa, and the chart shows that haplogroups are a convenient way of identifying different genealogical lines. For example, many of the Leigh/Lee lines in the United Kingdom are of haplogroup RB1. Some of the Leigh/Lee lines in the UK, though, are of haplogroup I. The chart shows that the RB1 and I haplogroups originated from different people in different parts of the world, and this leads to the conclusion that the Leigh/Lee lines of haplogroup I are not related in a genealogical time frame to the Leigh/Lee lines of haplogroup RB1. Of course, haplogroup I is a large group of people, and not all of the Leigh/Lee lines in that haplogroup are related to each other.

Click the picture for a larger view of the chart.



This site focuses on the genealogy of people of haplogroup I. The ancient people who became haplogroup I migrated towards Scandinavia. This migration spread the DNA of the migrants among local folks. Further spreading of the haplogroup I DNA occurred during the ice age by migrations from Scandinavia to the Balkans, southern France, Iberia (present day Spain and Portugal) and Italy. During the middle ages, the Vikings invaded a wide area in Europe for about 200 years and spread their DNA throughout that area. As a result, haplogroup I is found today in many countries in addition to the Scandinavian countries, but that haplogroup is not common in most countries outside of Scandinavia.

The common ancestor between two Y-DNA donors

People doing genealogical research will have identified their most distant ancestor. This ancestor might be themselves, a father, a grandfather, a great grandfather, or someone further back in their family tree. The researchers may want to know whether or not that ancestor is related to other persons who often but not always have the same surname. In doing traditional genealogical research, the researchers try to obtain written records that will tell them if their ancestor is related to the other persons. However, such records may be difficult to locate and may not even exist. Since the Y-DNA markers do exist for male descendants of the two lines being investigated, the researchers can compare the Y-DNA markers of a male descendant from each line to determine if the two persons are related in some way. The use of Y-DNA can't give an exact relationship between two people, but it can tell if it is likely the two persons are related via a common ancestor. People who are likely related to each other will have most of their Y-DNA values the same. The fewer the values that are different, the more likely that the two persons have a common ancestor.

Let's consider an example of the use of Y-DNA to determine if two people might be related. This is a real-life example, but the names and locations have been changed to protect the privacy of the two persons, both of whom are still living.

John Leigh lives in Colorado. His great grandfather on his father's side immigrated from Wales to the United States. John has researched his great grandfather's Leigh line in Wales and has identified his earliest known Leigh ancestor. John had his DNA tested with the hope that someone in England will have Y-DNA that is a close match with his Y-DNA, thus giving him a general idea of where in England his earliest ancestor might have lived.

Michael Lee lives in Virginia. He has researched his Lee line back to his grandfather on his father's side, but he has not been able to extend his family tree past his grandfather. Michael assumes that the Lee ancestor who immigrated to the United States came from England, but Michael does not know who that ancestor was or when he came to the United States. Michael had his DNA tested with the hope that someone who has identified the Lee immigrant will have Y-DNA that matches with his Y-DNA.

After both men had completed their DNA testing, they were notified by the company doing the testing that they have a close match with each other and that it is likely the two men have an ancestor who is common to both of the men. The presence of a common ancestor is important because the common ancestor provides a link between the two lines, thus establishing a relationship between the lines. Michael was surprised at his close match with John, because he never suspected that his family tree might go into Wales. John explained to Michael that the common ancestor might have lived before John's branch went to Wales. If this is the case, Michael's family tree might not go into Wales, even though John's family tree does go into Wales.

As I mentioned at the beginning of this post, this example is a real-life example of how DNA testing gave new information that brought two distant relatives together and gave one of the relatives an understanding that his family tree might go into Wales. Now, because it is likely that John and Michael have a common ancestor, they can assist each other in further research into the identity and whereabouts of the Lee immigrant who came to the United States. To help Michael with his research, John has identified several places in his family tree in Wales where sidelines could have sprouted from his main line and later furnished the Lee immigrant.

Genetic Distance

When two people learn that they might be related to each other because their Y-DNA have a close match, they wonder how close their relationship might be. Y-DNA results can not specify an exact relationship between the two people. The best it can do is give a general idea of their relationship. This is because the mutations that occur in the Y-DNA occur randomly. In addition, some values of Y-DNA mutate more often than other values.

Ancestry and FamilyTreeDNA have different ways of specifying an approximate relationship between two people. The Ancestry site gives the number of generations to the most recent common ancestor (MRCA) for a 50% probability. The probability factor is involved since Y-DNA can't give exact relationships. FamilyTreeDNA gives the genetic distance between the two people, where genetic distance is the number of differences in the values of the markers of the two men. For example, if the genetic distance is 2, there are two ways that that genetic distance could exist. The two men might have two DNA markers that differ by a value of 1 for each marker, or they might have one DNA marker that differs by a value of 2. Without additional DNA testing there is no way of knowing when and in which line(s) the mutations occurred.

This post gives information from FamilyTreeDNA that will help us estimate the closeness of a relationship based on the genetic distance of the two men. The more markers that were tested, the wider the range of genetic distance that can exist and still have a relationship. Here are links to the information from FamilyTreeDNA. The following information on relationships was taken from the FAQ at familytreedna.com (http://www.familytreedna.com/faq/answers/default.aspx?faqid=9#913) That page is worth reading, because it will clarify interpretations of
DNA results.

	Y-DNA12	Y-DNA25	Y-DNA37	Y-DNA67	Interpretation
Very Tightly Related	N/A	N/A	0	0	Your exact match means your relatedness is extremely close. Few people achieve this close level of a match. All confidence levels are well within the time frame that surnames were adopted in Western Europe.
Tightly Related	N/A	N/A	1	1-2	Few people achieve this close level of a match. All confidence levels are well within the time frame that surnames were adopted in Western Europe.
Related	0	0-1	2-3	3-6	Your degree of matching is within the range of most well established surname lineages in Western Europe. If you have tested with the Y-DNA12 or Y-DNA25 test, you should consider upgrading to additional STR markers. Doing so will improve your time to common ancestor calculations.
Possibly Related	1	2	4	7	Without additional evidence, it is unlikely that you share a common ancestor in recent genealogical times (1 to 6 generations). You may have a connection in more distant genealogical times (7 to 15 generations). If you have traditional genealogy records that indicate a relationship, then by testing additional individuals you will ether prove or disprove the connection.
Probably Not Related	2	3	5	8-9	It is highly unlikely that you share a common ancestor in genealogical times (1 to 15 generations). Should you have traditional genealogy records that indicate a relationship, then by testing additional individuals you will ether prove or disprove the connection. A careful review of your genealogical records is also recommended.
Not Related	3	4	6	10	You are not related on your Y-chromosome lineage within recent or distant genealogical times (1 to 15 generations).

As you use this information, don't "nit pick" the numbers. If the genetic distance is on the border of a possible relationship or no relationship, give yourself the benefit of the doubt and assume a possible relationship.

Even though Ancestry doesn't give genetic distance values, persons using Y-DNA values from Ancestry can still obtain genetic distance values by counting the number of markers that are different for the two persons, as explained above.

Finding and using the Leigh & Lee DNA information in this site

This site has information about each Leigh or Lee man who has had his Y-DNA tested by Ancestry or FamilyTreeDNA and has been identified as being haplogroup I. Review the information to see if the people fit into your family tree. If one or more persons do fit into your family tree, you can accept their DNA information as pertaining to your family, although members of your family may have slightly different values for their DNA markers due to mutations. To contact the men who had their Y-DNA tested, send emails to the contact persons given in the ysearch results (FamilyTreeDNA) or to the descendants who had their DNA tested by Ancestry (as explained in the months of May and June).

Note about Ancestry: The Lee DNA Genealogy Project used to have a guest account that would allow you to view the records in the group. The login information, which is still given in the page for the group, doesn't work. You apparently will have to request a membership in the group as a researcher, or buy a kit and have your Y-DNA tested.

DNA isn't a Silver Bullet

DNA can give you general information about your ancestors, but you will still need to verify that information with traditional research in genealogical documents. The information you receive from the descendants will, hopefully, give you ideas about where to look for additional genealogical documents, and your research in those documents will, hopefully, give you more detailed information about your ancestors.

If none of the people fit into your family tree, information provided by the descendants may help you locate new genealogical documents that may allow you to connect to one or more of the people.

Navigating this Site

Because this site is actually a blog, the pages of this site are organized into years and months. The links to DNA testing of individual people are placed into particular months, as follows.

• September 2009 - Introduction to this site. Links to various pages of this site
  

• August 2009 - Leigh lines from FamilyTree

• July 2009 - Lee lines from FamilyTree

• June 2009 - Leigh lines from Ancestry

• May 2009 - Lee lines from Ancestry

Using ysearch to search the ysearch database

FamilyTreeDNA has a free website called ysearch.org that can be used to search the ysearch database of persons who have had their Y-DNA tested. The ysearch database contains marker values that have been transferred from the FamilyTreeDNA database of test-values. Not all persons who are tested have their marker-values transferred to ysearch. You can use ysearch to search by last name or by genetic matches with a specific ysearch ID.

Search by Last Name

This search can be performed by anyone. You enter the last name and the regions of the world you went tested. The Results page will show the name you searched and in the Name or Variants column a link to all of the records that were found. Click the link and you will get a page with all of the records that were found. Have a little patience, because the search may take a few seconds.

The first column in your results is Compare, and that column has a check box for each record found. Click the check box for all of the records you want to keep (if you want most of the records, click Check All and then click the ones you don't want to keep). When you have selected all of the records that you want to keep, click the name of the column (Compare) which is underlined to show it is a link. Choose if you want to show comparative Y-DNA results or genetic distances. Your report will be created, and you can print it.

Search for Genetic Matches

Enter the ysearch ID of the man who will be the reference for the genetic matches. You will then be asked to enter search parameters. Keep the default that the user tested at least 8 of the markers that were tested for the reference person. Nobody tests less than 12 markers, so all people who were tested should be included in the results. You can specify a maximum for the genetic distances to be reported, or you can specify a maximum genetic distance of 1 per marker. To begin with, choose the second choice of 1 per marker. Choose how you want the last name to limit the search. Choose how you want haplogroups to limit the search, and choose the regions of the world you want included in the search. Then click the Search button.

This search can be performed by anyone who has access to a ysearch ID of a man who had his Y-DNA tested by FamilyTreeDNA. For example, women can use the ID of their husbands or of male relatives to do genetic matches with that man. Have a little patience, because the search may take a few seconds.

The first column in the results is Compare, and that column has a check box for each record found. Click the check box for all of the records you want to keep (if you want most of the records, click Check All and then click the ones you don't want to keep). When you have selected all of the records that you want to keep, click the name of the column (Compare) which is underlined to show it is a link. Select if you want to show comparative Y-DNA results or genetic distances. Your report will be created, and you can print it.

Create a New User

If you have recently had the Y-DNA of a male family member tested by FamilyTreeDNA, you can go to ysearch and click the Create a New User tab to create an account for the person who was tested. Then, you can click a field in that person's account at the FTDNA web site to have his test results (marker values) automatically sent to ysearch. When you first create the account on ysearch, you will be given a ysearch ID, and you can use that ID to perform genetic matches.

Other Tabs

There are a few other tabs in ysearch that you can explore at your leisure.

A useful technique for data from Ancestry

In displaying names in its site, Ancestry groups the data from its testing into subgroups. Each subgroup has names that the server thinks are closely related to each other. It is helpful if you reorder the data in a subgroup to make your person the reference person for that subgroup. By doing this, the number of generations in the MRCA column will be relative to your person, and having your person at the top of the list makes it easier to visually compare the Y-DNA markers of your person with the markers of those who are most closely related to him.

Here is the procedure to make your person the reference for the subgroup.

1. Place the mouse cursor on the name of your person. You will see a down arrow at the left of the name.
2. Click the down arrow and select "Make this person the reference person"

The names in that subgroup will be reordered with your person at the top of the list, and all of the MRCA numbers will be relative to your person.

Another option is to change the View field at the top of the page to be "Sorted List" instead of "Genetic Subgroups (default)". This will remove the subgroups and will place all of the names in one list. You can make your person the reference person, as explained above, and you can check if persons in other subgroups are closely related to your person. However, this procedure does not reorder the list by MRCA number, and persons most closely related to your person will likely be scattered throughout the list. In addition, many of the MRCA numbers may be a dash (-) due, I assume, to the number being too large to fit in the field.

Uploading your markers to ysearch

Many of you who visit this site had your Y-DNA tested by a company other than FamilyTreeDNA. Yet, you would like to use ysearch to compare your markers with those who were tested by FamilyTreeDNA. It is possible to upload your markers to the ysearch database, and this page gives you the step-by-step procedure. I recommend that you do this to give you access to a larger reservoir of individuals who have been tested.

1. Go to ysearch.org and click the Create a New User link to create your account. This step gives you an empty account on ysearch, that is, an account with no marker-values.
2. Manually enter your Y-DNA values from the company that tested your DNA. Be careful in doing this, because the order of the values in ysearch may not be the same as the order of the values given you by the lab who tested your DNA.
   
3. Correct certain values as given in the correction page of ysearch. This correction is necessary, because different labs have slightly different ways of testing your DNA.
   
   NOTE: Due to a recent change made by Ancestry, do not subtract 11 from the value for the GATA-H4 marker.
   

You now have your marker-values uploaded to the ysearch database, and you can use ysearch to compare your values with those of persons who were tested by FamilyTreeDNA. By doing this upload, you will be able to compare your Y-DNA with a much greater range of people.

If you do upload values to ysearch, please email me at genealogy (at) welshleigh (dot) org so I can add your new ysearch ID to the Clearing House.